Detection of post-vaccination enhanced dengue virus infection in macaques: An improved model for early assessment of dengue vaccines

The need for improved dengue vaccines remains since the only licensed vaccine, Dengvaxia, shows variable efficacy depending on the infecting dengue virus (DENV) type, and increases the risk of hospitalization for severe dengue in children not exposed to DENV before vaccination. Here, we developed a...

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Vydáno v:PLoS Pathog
Hlavní autoři: Borges, Maria Beatriz, Marchevsky, Renato Sergio, Carvalho Pereira, Renata, da Silva Mendes, Ygara, Almeida Mendes, Luiz Gustavo, Diniz-Mendes, Leonardo, Cruz, Michael A., Tahmaoui, Ouafaâ, Baudart, Sébastien, Freire, Marcos, Homma, Akira, Schneider-Ohrum, Kirsten, Vaughn, David W., Vanloubbeeck, Yannick, Lorin, Clarisse, Malice, Marie-Pierre, Caride, Elena, Warter, Lucile
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497418/
https://ncbi.nlm.nih.gov/pubmed/31009499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007721
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