Characterization of recent and minimally passaged Brazilian dengue viruses inducing robust infection in rhesus macaques

The macaque is widely accepted as a suitable model for preclinical characterization of dengue vaccine candidates. However, the only vaccine for which both preclinical and clinical efficacy results were reported so far showed efficacy levels that were substantially different between macaques and huma...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Borges, Maria Beatriz, Marchevsky, Renato Sergio, Mendes, Ygara S., Mendes, Luiz Gustavo, Duarte, Ana Claudia, Cruz, Michael, de Filippis, Ana Maria Bispo, Vasconcelos, Pedro Fernando C., Freire, Marcos, Homma, Akira, Mossman, Sally, Lepine, Edith, Vanloubbeeck, Yannick, Lorin, Clarisse, Malice, Marie-Pierre, Caride, Elena, Warter, Lucile
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919018/
https://ncbi.nlm.nih.gov/pubmed/29694440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196311
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