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Higher anti‐tumour efficacy of platinum(IV) complex LA‐12 is associated with its ability to bypass M‐phase entry block induced in oxaliplatin‐treated human colon cancer cells

OBJECTIVES: Therapeutic potential of conventionally used platinum‐based drugs in treatment of colorectal tumours has been limited due to high incidence of tumour resistance to them and to their severe side effects. This evokes a search for more suitable anti‐cancer drugs. We have compared ability of...

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Détails bibliographiques
Publié dans:Cell Prolif
Auteurs principaux: Vondálová Blanářová, O., Jelínková, I., Hyršlová Vaculová, A., Sova, P., Hofmanová, J., Kozubík, A.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496914/
https://ncbi.nlm.nih.gov/pubmed/24118195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12061
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