Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells

Although Chk1 kinase inhibitors are currently under clinical investigation as effective cancer cell sensitizers to the cytotoxic effects of numerous chemotherapeutics, there is still a considerable uncertainty regarding their role in modulation of anticancer potential of platinum-based drugs. Here w...

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Bibliographic Details
Published in:Neoplasia
Main Authors: Herůdková, Jarmila, Paruch, Kamil, Khirsariya, Prashant, Souček, Karel, Krkoška, Martin, Vondálová Blanářová, Olga, Sova, Petr, Kozubík, Alois, Hyršlová Vaculová, Alena
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2017
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Original article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591453/
https://ncbi.nlm.nih.gov/pubmed/28888100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.08.002
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