Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells

Although Chk1 kinase inhibitors are currently under clinical investigation as effective cancer cell sensitizers to the cytotoxic effects of numerous chemotherapeutics, there is still a considerable uncertainty regarding their role in modulation of anticancer potential of platinum-based drugs. Here w...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Herůdková, Jarmila, Paruch, Kamil, Khirsariya, Prashant, Souček, Karel, Krkoška, Martin, Vondálová Blanářová, Olga, Sova, Petr, Kozubík, Alois, Hyršlová Vaculová, Alena
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2017
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591453/
https://ncbi.nlm.nih.gov/pubmed/28888100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.08.002
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