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Higher anti‐tumour efficacy of platinum(IV) complex LA‐12 is associated with its ability to bypass M‐phase entry block induced in oxaliplatin‐treated human colon cancer cells

OBJECTIVES: Therapeutic potential of conventionally used platinum‐based drugs in treatment of colorectal tumours has been limited due to high incidence of tumour resistance to them and to their severe side effects. This evokes a search for more suitable anti‐cancer drugs. We have compared ability of...

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Publicado en:Cell Prolif
Autores principales: Vondálová Blanářová, O., Jelínková, I., Hyršlová Vaculová, A., Sova, P., Hofmanová, J., Kozubík, A.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496914/
https://ncbi.nlm.nih.gov/pubmed/24118195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12061
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