Over‐expression of cyclin D1 regulates Cdk4 protein synthesis

Abstract.  Increased Cdk4 expression occurs coincident with over‐expression of cyclin D1 in many human tumours and tumourigenic mouse models. Here, we investigate both in vivo and in vitro the mechanism by which Cdk4 expression is regulated in the context of cyclin D1 over‐expression. Cdk4 mRNA leve...

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Publicado en:Cell Prolif
Main Authors: Parker, M. A., Deane, N. G., Thompson, E. A., Whitehead, R. H., Mithani, S. K., Washington, M. K., Datta, P. K., Dixon, D. A., Beauchamp, R. D.
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd. 2003
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496860/
https://ncbi.nlm.nih.gov/pubmed/14710852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2003.00290.x
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