Over‐expression of cyclin D1 regulates Cdk4 protein synthesis

Abstract.  Increased Cdk4 expression occurs coincident with over‐expression of cyclin D1 in many human tumours and tumourigenic mouse models. Here, we investigate both in vivo and in vitro the mechanism by which Cdk4 expression is regulated in the context of cyclin D1 over‐expression. Cdk4 mRNA leve...

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Bibliographic Details
Published in:Cell Prolif
Main Authors: Parker, M. A., Deane, N. G., Thompson, E. A., Whitehead, R. H., Mithani, S. K., Washington, M. K., Datta, P. K., Dixon, D. A., Beauchamp, R. D.
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd. 2003
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496860/
https://ncbi.nlm.nih.gov/pubmed/14710852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2003.00290.x
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