Over‐expression of cyclin D1 regulates Cdk4 protein synthesis

Abstract.  Increased Cdk4 expression occurs coincident with over‐expression of cyclin D1 in many human tumours and tumourigenic mouse models. Here, we investigate both in vivo and in vitro the mechanism by which Cdk4 expression is regulated in the context of cyclin D1 over‐expression. Cdk4 mRNA leve...

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Bibliografski detalji
Izdano u:Cell Prolif
Glavni autori: Parker, M. A., Deane, N. G., Thompson, E. A., Whitehead, R. H., Mithani, S. K., Washington, M. K., Datta, P. K., Dixon, D. A., Beauchamp, R. D.
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd. 2003
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496860/
https://ncbi.nlm.nih.gov/pubmed/14710852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2003.00290.x
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