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Reduced level of the spindle checkpoint protein BUB1B is associated with aneuploidy in colorectal cancers

Abstract.  Objectives: The majority of solid human malignancies demonstrate DNA aneuploidy as a consequence of chromosomal instability. We wanted to investigate whether Aurora A, Aurora B, BUB1B and Mad2 were associated with the development of aneuploidy in colorectal adenocarcinomas as suggested by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Prolif
Hauptverfasser: Burum‐Auensen, E., DeAngelis, P. M., Schjølberg, A. R., Røislien, J., Mjåland, O., Clausen, O. P. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496857/
https://ncbi.nlm.nih.gov/pubmed/18699967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2008.00539.x
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