Reduced level of the spindle checkpoint protein BUB1B is associated with aneuploidy in colorectal cancers

Abstract.  Objectives: The majority of solid human malignancies demonstrate DNA aneuploidy as a consequence of chromosomal instability. We wanted to investigate whether Aurora A, Aurora B, BUB1B and Mad2 were associated with the development of aneuploidy in colorectal adenocarcinomas as suggested by...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Burum‐Auensen, E., DeAngelis, P. M., Schjølberg, A. R., Røislien, J., Mjåland, O., Clausen, O. P. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496857/
https://ncbi.nlm.nih.gov/pubmed/18699967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2008.00539.x
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