Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis

BACKGROUND: Long term ulcerative colitis (UC) increases the risk of colorectal cancer (CRC). DNA aneuploidy is a common feature of both dysplastic and non‐dysplastic colonic epithelia from patients with longstanding UC, and is regarded as an early sign of possible malignant transformation. The spind...

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Autores principales: Burum‐Auensen, E, DeAngelis, P M, Schjølberg, A R, Røislien, Jo, Andersen, S N, Clausen, O P F
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Group 2007
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095563/
https://ncbi.nlm.nih.gov/pubmed/17322345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2006.044305
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