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Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors

BACKGROUND: Testicular germ cell tumors (TGCTs) are characterized by an aneuploid DNA content. Aberrant expression of spindle proteins such as the Aurora kinases and the spindle checkpoint proteins MAD2 and BUB1B, are thought to contribute to the development of chromosomal instability and DNA aneupl...

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Bibliografiske detaljer
Main Authors: Burum-Auensen, Espen, Skotheim, Rolf I., Schjølberg, Aasa R., Røislien, Jo, Lothe, Ragnhild A., Clausen, Ole Petter F.
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856146/
https://ncbi.nlm.nih.gov/pubmed/20411023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.60358
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