Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors

BACKGROUND: Testicular germ cell tumors (TGCTs) are characterized by an aneuploid DNA content. Aberrant expression of spindle proteins such as the Aurora kinases and the spindle checkpoint proteins MAD2 and BUB1B, are thought to contribute to the development of chromosomal instability and DNA aneupl...

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Bibliographic Details
Main Authors: Burum-Auensen, Espen, Skotheim, Rolf I., Schjølberg, Aasa R., Røislien, Jo, Lothe, Ragnhild A., Clausen, Ole Petter F.
Format: Artigo
Language:Inglês
Published: Medknow Publications 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856146/
https://ncbi.nlm.nih.gov/pubmed/20411023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.60358
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