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Monitoring the fidelity of mitotic chromosome segregation by the spindle assembly checkpoint

Accurate chromosome segregation relies on activity of the spindle assembly checkpoint, a surveillance mechanism that prevents premature anaphase onset until all chromosomes are properly attached to the mitotic spindle apparatus and aligned at the metaphase plate. Defects in this mechanism contribute...

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Publicat a:Cell Prolif
Autors principals: Silva, P., Barbosa, J., Nascimento, A. V., Faria, J., Reis, R., Bousbaa, H.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496767/
https://ncbi.nlm.nih.gov/pubmed/21951282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2011.00767.x
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