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JLK1486, a N,N‐[(8‐hydroxyquinoline)methyl]‐substituted benzylamine analogue, inhibits melanoma proliferation and induces autophagy

OBJECTIVES: To investigate anti‐proliferatory activity of a selected N,N‐[(8‐hydroxyquinoline)methyl]‐substituted benzylamine (JLK1486) on melanoma cells and to characterize its mechanism of cell population growth inhibition. MATERIALS AND METHODS: In vitro cultures of B16F10 (mouse melanoma) cells...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Koekemoer, T. C., van de Venter, M., Kraus, J.‐L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496716/
https://ncbi.nlm.nih.gov/pubmed/25139616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12127
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