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Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus
Transgenic mice expressing MyrAkt from a proximal Lck promoter construct develop thymomas at an early age, whereas transgenic mice expressing constitutively active Lck-AktE40K develop primarily tumors of the peripheral lymphoid organs later in life. The thymus of 6- to 8-week-old MyrAkt transgenic m...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC64967/ https://ncbi.nlm.nih.gov/pubmed/11752445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231467698 |
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