Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus

Transgenic mice expressing MyrAkt from a proximal Lck promoter construct develop thymomas at an early age, whereas transgenic mice expressing constitutively active Lck-AktE40K develop primarily tumors of the peripheral lymphoid organs later in life. The thymus of 6- to 8-week-old MyrAkt transgenic m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Malstrom, Scott, Tili, Esmerina, Kappes, Dietmar, Ceci, Jeffrey D., Tsichlis, Philip N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2001
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC64967/
https://ncbi.nlm.nih.gov/pubmed/11752445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231467698
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak