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Overexpression of MyrAkt1 in Endothelial Cells Leads to Erythropoietin- and BMP4-Independent Splenic Erythropoiesis in Mice

Under steady state conditions, erythropoiesis occurs in the bone marrow. However, in mice, stress or tissue hypoxia results in increased erythropoiesis in the spleen. There is increasing evidence that the hematopoietic microenvironment, including endothelial cells, plays an important role in regulat...

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Bibliografische gegevens
Hoofdauteurs: O’Donnell, Rebekah K., Goldstein, Whitney E., Perruzzi, Carole, Benjamin, Laura E., Aird, William
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557261/
https://ncbi.nlm.nih.gov/pubmed/23383068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055095
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