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Overexpression of MyrAkt1 in Endothelial Cells Leads to Erythropoietin- and BMP4-Independent Splenic Erythropoiesis in Mice

Under steady state conditions, erythropoiesis occurs in the bone marrow. However, in mice, stress or tissue hypoxia results in increased erythropoiesis in the spleen. There is increasing evidence that the hematopoietic microenvironment, including endothelial cells, plays an important role in regulat...

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Detalhes bibliográficos
Main Authors: O’Donnell, Rebekah K., Goldstein, Whitney E., Perruzzi, Carole, Benjamin, Laura E., Aird, William
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557261/
https://ncbi.nlm.nih.gov/pubmed/23383068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055095
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