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A FASII Inhibitor Prevents Staphylococcal Evasion of Daptomycin by Inhibiting Phospholipid Decoy Production

Daptomycin is a treatment of last resort for serious infections caused by drug-resistant Gram-positive pathogens, such as methicillin-resistant Staphylococcus aureus. We have shown recently that S. aureus can evade daptomycin by releasing phospholipid decoys that sequester and inactivate the antibio...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Pee, Carmen J. E., Pader, Vera, Ledger, Elizabeth V. K., Edwards, Andrew M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496159/
https://ncbi.nlm.nih.gov/pubmed/30718253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02105-18
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