Inhibitors of Pantothenate Kinase: Novel Antibiotics for Staphylococcal Infections

Pantothenate kinase (CoaA) catalyzes the first step of the coenzyme A biosynthetic pathway. Here we report the identification of the Staphylococcus aureus coaA gene and characterization of the enzyme. We have also identified a series of low-molecular-weight compounds which are effective inhibitors o...

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Bibliografiset tiedot
Päätekijät: Choudhry, Anthony E., Mandichak, Tracy L., Broskey, John P., Egolf, Richard W., Kinsland, Cynthia, Begley, Tadhg P., Seefeld, Mark A., Ku, Thomas W., Brown, James R., Zalacain, Magdalena, Ratnam, Kapila
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2003
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Mechanisms of Action: Physiological Effects
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC155856/
https://ncbi.nlm.nih.gov/pubmed/12760898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.6.2051-2055.2003
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