Cycloserine Population Pharmacokinetics and Pharmacodynamics in Patients with Tuberculosis

Limited pharmacokinetic/pharmacodynamic (PK/PD) data exist on cycloserine in tuberculosis (TB) patients. We pooled several studies into a large PK data set to estimate the population PK parameters for cycloserine in TB patients. We also performed simulations to provide insight into optimizing the do...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Alghamdi, Wael A., Alsultan, Abdullah, Al-Shaer, Mohammad H., An, Guohua, Ahmed, Shahriar, Alkabab, Yosra, Banu, Sayera, Barbakadze, Ketevan, Houpt, Eric, Kipiani, Maia, Mikiashvili, Lali, Schmidt, Stephan, Heysell, Scott K., Kempker, Russell R., Cegielski, J. Peter, Peloquin, Charles A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
Onderwerpen:
Clinical Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496076/
https://ncbi.nlm.nih.gov/pubmed/30858211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00055-19
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