Cycloserine Population Pharmacokinetics and Pharmacodynamics in Patients with Tuberculosis

Limited pharmacokinetic/pharmacodynamic (PK/PD) data exist on cycloserine in tuberculosis (TB) patients. We pooled several studies into a large PK data set to estimate the population PK parameters for cycloserine in TB patients. We also performed simulations to provide insight into optimizing the do...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Alghamdi, Wael A., Alsultan, Abdullah, Al-Shaer, Mohammad H., An, Guohua, Ahmed, Shahriar, Alkabab, Yosra, Banu, Sayera, Barbakadze, Ketevan, Houpt, Eric, Kipiani, Maia, Mikiashvili, Lali, Schmidt, Stephan, Heysell, Scott K., Kempker, Russell R., Cegielski, J. Peter, Peloquin, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496076/
https://ncbi.nlm.nih.gov/pubmed/30858211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00055-19
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