Apotransferrin in Combination with Ciprofloxacin Slows Bacterial Replication, Prevents Resistance Amplification, and Increases Antimicrobial Regimen Effect

There has been renewed interest in combining traditional small-molecule antimicrobial agents with nontraditional therapies to potentiate antimicrobial effects. Apotransferrin, which decreases iron availability to microbes, is one such approach. We conducted a 48-h one-compartment in vitro infection...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Ambrose, Paul G., VanScoy, Brian D., Luna, Brian M., Yan, Jun, Ulhaq, Amber, Nielsen, Travis B., Rudin, Sue, Hujer, Kristine, Bonomo, Robert A., Actis, Luis, Skaar, Eric, Spellberg, Brad
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496049/
https://ncbi.nlm.nih.gov/pubmed/30782989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00112-19
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