Differential Effects of Linezolid and Ciprofloxacin on Toxin Production by Bacillus anthracis in an In Vitro Pharmacodynamic System

Bacillus anthracis causes anthrax. Ciprofloxacin is a gold standard for the treatment of anthrax. Previously, using the non-toxin-producing ΔSterne strain of B. anthracis, we demonstrated that linezolid was equivalent to ciprofloxacin for reducing the total (vegetative and spore) bacterial populatio...

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Detalhes bibliográficos
Main Authors: Louie, Arnold, VanScoy, Brian D., Heine, Henry S., Liu, Weiguo, Abshire, Terry, Holman, Kari, Kulawy, Robert, Brown, David L., Drusano, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256020/
https://ncbi.nlm.nih.gov/pubmed/22064542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05724-11
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