Assessment of epidermal growth factor receptor (EGFR, ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb(®), GW572016) in an expanded panel of human normal and tumour cell lines

Abstract.  Objective: Lapatinib (Tykerb(®), GW572016), a potent inhibitor of the catalytic activities of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) (ErbB2), inhibits population growth of selected EGFR and HER2 overexpressing cell lines. Previous studi...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Rusnak, D. W., Alligood, K. J., Mullin, R. J., Spehar, G. M., Arenas‐Elliott, C., Martin, A.‐M., Degenhardt, Y., Rudolph, S. K., Jr Haws, T. F., Hudson‐Curtis, B. L., Gilmer, T. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2007
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495710/
https://ncbi.nlm.nih.gov/pubmed/17635524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2007.00455.x
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