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μ‐Opioid Receptor Attenuates Aβ Oligomers‐Induced Neurotoxicity Through mTOR Signaling

AIMS: μ‐opioid receptor (OPRM1) exerts many functions such as antinociception, neuroprotection, and hippocampal plasticity. A body of evidence has shown that OPRM1 activation could stimulate downstream effectors of mechanistic/mammalian target of rapamycin (mTOR). However, it is not clear whether OP...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:CNS Neurosci Ther
Hauptverfasser: Wang, Yan, Wang, Yan‐Xia, Liu, Ting, Law, Ping‐Yee, Loh, Horace H., Qiu, Yu, Chen, Hong‐Zhuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495561/
https://ncbi.nlm.nih.gov/pubmed/25146548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12316
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