Silencing dishevelled‐1 sensitizes paclitaxel‐resistant human ovarian cancer cells via AKT/GSK‐3β/β‐catenin signalling

OBJECTIVES: Expression of dishevelled‐1 (DVL1) has recently been linked to cancer progression, however, its role in resistance to cancer therapy is unclear. In this study, we aimed to explore the function of DVL1 in paclitaxel‐resistant human ovarian cancer cells. MATERIALS AND METHODS: The MTT assa...

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Publicat a:Cell Prolif
Autors principals: Zhang, Kun, Song, Haixing, Yang, Ping, Dai, Xiaozhen, Li, Ya, Wang, Lan, Du, Jun, Pan, Kejian, Zhang, Tao
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495546/
https://ncbi.nlm.nih.gov/pubmed/25643607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12161
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