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Silencing dishevelled‐1 sensitizes paclitaxel‐resistant human ovarian cancer cells via AKT/GSK‐3β/β‐catenin signalling

OBJECTIVES: Expression of dishevelled‐1 (DVL1) has recently been linked to cancer progression, however, its role in resistance to cancer therapy is unclear. In this study, we aimed to explore the function of DVL1 in paclitaxel‐resistant human ovarian cancer cells. MATERIALS AND METHODS: The MTT assa...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Zhang, Kun, Song, Haixing, Yang, Ping, Dai, Xiaozhen, Li, Ya, Wang, Lan, Du, Jun, Pan, Kejian, Zhang, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495546/
https://ncbi.nlm.nih.gov/pubmed/25643607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12161
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