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Silencing dishevelled‐1 sensitizes paclitaxel‐resistant human ovarian cancer cells via AKT/GSK‐3β/β‐catenin signalling

OBJECTIVES: Expression of dishevelled‐1 (DVL1) has recently been linked to cancer progression, however, its role in resistance to cancer therapy is unclear. In this study, we aimed to explore the function of DVL1 in paclitaxel‐resistant human ovarian cancer cells. MATERIALS AND METHODS: The MTT assa...

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Vydáno v:Cell Prolif
Hlavní autoři: Zhang, Kun, Song, Haixing, Yang, Ping, Dai, Xiaozhen, Li, Ya, Wang, Lan, Du, Jun, Pan, Kejian, Zhang, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495546/
https://ncbi.nlm.nih.gov/pubmed/25643607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12161
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