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DNA supercoiling allows enhancer action over a large distance

Enhancers are regulatory DNA elements that can activate their genomic targets over a large distance. The mechanism of enhancer action over large distance is unknown. Activation of the glnAp2 promoter by NtrC-dependent enhancer in Escherichia coli was analyzed by using a purified system supporting mu...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Liu, Ye, Bondarenko, Vladimir, Ninfa, Alexander, Studitsky, Vasily M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2001
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11742093/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.261477898
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