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DNA supercoiling allows enhancer action over a large distance

Enhancers are regulatory DNA elements that can activate their genomic targets over a large distance. The mechanism of enhancer action over large distance is unknown. Activation of the glnAp2 promoter by NtrC-dependent enhancer in Escherichia coli was analyzed by using a purified system supporting mu...

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Detalhes bibliográficos
Main Authors: Liu, Ye, Bondarenko, Vladimir, Ninfa, Alexander, Studitsky, Vasily M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC64953/
https://ncbi.nlm.nih.gov/pubmed/11742093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261477898
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