Steroidal antibiotics are antimetabolites of Acanthamoeba steroidogenesis with phylogenetic implications

Pathogenic organisms may be sensitive to inhibitors of sterol biosynthesis, which carry antimetabolite properties, through manipulation of the key enzyme, sterol methyltransferase (SMT). Here, we isolated natural suicide substrates of the ergosterol biosynthesis pathway, cholesta-5,7,22,24-tetraenol...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Lipid Res
मुख्य लेखकों: Zhou, Wenxu, Ramos, Emilio, Zhu, Xunlu, Fisher, Paxtyn M., Kidane, Medhanie E., Vanderloop, Boden H., Thomas, Crista D., Yan, Juqiang, Singha, Ujjal, Chaudhuri, Minu, Nagel, Michael T., Nes, W. David
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Biochemistry and Molecular Biology 2019
विषय:
Research Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495176/
https://ncbi.nlm.nih.gov/pubmed/30709898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M091587
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