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Arp2/3 complex requires hydrolyzable ATP for nucleation of new actin filaments

The Arp2/3 complex, a seven-subunit protein complex containing two actin-related proteins, Arp2 and Arp3, initiates formation of actin filament networks in response to intracellular signals. The molecular mechanism of filament nucleation, however, is not well understood. Arp2 and Arp3 are predicted...

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Detalles Bibliográficos
Main Authors: Dayel, Mark J., Holleran, Elizabeth A., Mullins, R. Dyche
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC64951/
https://ncbi.nlm.nih.gov/pubmed/11752435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261419298
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