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Capping Protein Increases the Rate of Actin-based Motility by Promoting Filament Nucleation by the Arp2/3 Complex

Capping protein is an integral component of Arp2/3-nucleated actin networks that drive amoeboid motility. Increasing the concentration of capping protein, which caps barbed ends of actin filaments and prevents elongation, increases the rate of actin-based motility in vivo and in vitro. We studied th...

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Autori principali: Akin, Orkun, Mullins, R. Dyche
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576297/
https://ncbi.nlm.nih.gov/pubmed/18510928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.04.011
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