Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments

The actin-related protein 2/3 (Arp2/3) complex is the primary nucleator of new actin filaments in most crawling cells. Nucleation-promoting factors (NPFs) of the Wiskott-Aldrich syndrome protein (WASP)/Scar family are the currently recognized activators of the Arp2/3 complex. We now report that the...

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Main Authors: LeClaire, Lawrence L., Baumgartner, Martin, Iwasa, Janet H., Mullins, R. Dyche, Barber, Diane L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2008
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518704/
https://ncbi.nlm.nih.gov/pubmed/18725535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200802145
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