Large-Scale Generation and Characterization of Homogeneous Populations of Migratory Cortical Interneurons from Human Pluripotent Stem Cells

During development, cortical interneurons (cINs) are generated from the ventral telencephalon, robustly migrate to the dorsal telencephalon, make local synaptic connections, and critically regulate brain circuitry by inhibiting other neurons. Thus, their abnormality is associated with various brain...

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Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Ni, Peiyan, Noh, Haneul, Shao, Zhicheng, Zhu, Qian, Guan, Youxin, Park, Joshua J., Arif, Fatima, Park, James M., Abani, Chiderah, Beaudreault, Cameron, Park, Joy S., Berry, Elizabeth, Moghadam, Alexander, Stanton, Patric, Hutchinson, John N., Andrews, Bill, Faux, Clare, Parnevelas, John, Eisenberg, Leonard M., Park, Kyungjoon, Bolshakov, Vadim Y., Chung, Sangmi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495066/
https://ncbi.nlm.nih.gov/pubmed/31061832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.04.002
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