Large-Scale Generation and Characterization of Homogeneous Populations of Migratory Cortical Interneurons from Human Pluripotent Stem Cells

During development, cortical interneurons (cINs) are generated from the ventral telencephalon, robustly migrate to the dorsal telencephalon, make local synaptic connections, and critically regulate brain circuitry by inhibiting other neurons. Thus, their abnormality is associated with various brain...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Ni, Peiyan, Noh, Haneul, Shao, Zhicheng, Zhu, Qian, Guan, Youxin, Park, Joshua J., Arif, Fatima, Park, James M., Abani, Chiderah, Beaudreault, Cameron, Park, Joy S., Berry, Elizabeth, Moghadam, Alexander, Stanton, Patric, Hutchinson, John N., Andrews, Bill, Faux, Clare, Parnevelas, John, Eisenberg, Leonard M., Park, Kyungjoon, Bolshakov, Vadim Y., Chung, Sangmi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495066/
https://ncbi.nlm.nih.gov/pubmed/31061832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.04.002
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