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Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo

Vitiligo is an autoimmune disease of the skin mediated by CD8(+) T cells that kill melanocytes and create white spots. Skin lesions in vitiligo frequently return after discontinuing conventional treatments, supporting the hypothesis that autoimmune memory is formed at these locations. We found that...

詳細記述

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書誌詳細
出版年:Sci Transl Med
主要な著者: Richmond, Jillian M., Strassner, James P., Zapata, Lucio, Garg, Madhuri, Riding, Rebecca L., Refat, Maggi A., Fan, Xueli, Azzolino, Vincent, Tovar-Garza, Andrea, Tsurushita, Naoya, Pandya, Amit G., Tso, J. Yun, Harris, John E.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495055/
https://ncbi.nlm.nih.gov/pubmed/30021889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aam7710
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