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Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo

Vitiligo is an autoimmune disease of the skin mediated by CD8(+) T cells that kill melanocytes and create white spots. Skin lesions in vitiligo frequently return after discontinuing conventional treatments, supporting the hypothesis that autoimmune memory is formed at these locations. We found that...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Transl Med
Κύριοι συγγραφείς: Richmond, Jillian M., Strassner, James P., Zapata, Lucio, Garg, Madhuri, Riding, Rebecca L., Refat, Maggi A., Fan, Xueli, Azzolino, Vincent, Tovar-Garza, Andrea, Tsurushita, Naoya, Pandya, Amit G., Tso, J. Yun, Harris, John E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495055/
https://ncbi.nlm.nih.gov/pubmed/30021889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aam7710
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