Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo

Vitiligo is an autoimmune disease of the skin mediated by CD8(+) T cells that kill melanocytes and create white spots. Skin lesions in vitiligo frequently return after discontinuing conventional treatments, supporting the hypothesis that autoimmune memory is formed at these locations. We found that...

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Detalles Bibliográficos
Publicado en:Sci Transl Med
Main Authors: Richmond, Jillian M., Strassner, James P., Zapata, Lucio, Garg, Madhuri, Riding, Rebecca L., Refat, Maggi A., Fan, Xueli, Azzolino, Vincent, Tovar-Garza, Andrea, Tsurushita, Naoya, Pandya, Amit G., Tso, J. Yun, Harris, John E.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495055/
https://ncbi.nlm.nih.gov/pubmed/30021889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aam7710
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