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Oxygen dissociation from ferrous oxygenated human hemoglobin:haptoglobin complexes confirms that in the R-state α and β chains are functionally heterogeneous

The adverse effects of extra-erythrocytic hemoglobin (Hb) are counterbalanced by several plasma proteins devoted to facilitate the clearance of free heme and Hb. In particular, haptoglobin (Hp) traps the αβ dimers of Hb, which are delivered to the reticulo-endothelial system by CD163 receptor-mediat...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Ascenzi, Paolo, Polticelli, Fabio, Coletta, Massimiliano
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494993/
https://ncbi.nlm.nih.gov/pubmed/31043649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43190-x
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