Peroxidase Activity of Hemoglobin·Haptoglobin Complexes: COVALENT AGGREGATION AND OXIDATIVE STRESS IN PLASMA AND MACROPHAGES

As a hemoprotein, hemoglobin (Hb) can, in the presence of H(2)O(2), act as a peroxidase. In red blood cells, this activity is regulated by the reducing environment. For stroma-free Hb this regulation is lost, and the potential for Hb to become a peroxidase is high and further increased by inflammato...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Kapralov, Alexandr, Vlasova, Irina I., Feng, Weihong, Maeda, Akihiro, Walson, Karen, Tyurin, Vladimir A., Huang, Zhentai, Aneja, Rajesh K., Carcillo, Joseph, Bayır, Hülya, Kagan, Valerian E.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2009
الموضوعات:
Enzyme Catalysis and Regulation
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781594/
https://ncbi.nlm.nih.gov/pubmed/19740759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045567
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