Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections

Analysis of entire transparent rodent bodies after clearing could provide holistic biological information in health and disease, but reliable imaging and quantification of fluorescent protein signals deep inside the tissues remained a challenge. Here, we developed vDISCO, a pressure driven, nanobody...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Neurosci
Prif Awduron: Cai, Ruiyao, Pan, Chenchen, Ghasemigharagoz, Alireza, Todorov, Mihail Ivilinov, Förstera, Benjamin, Zhao, Shan, Bhatia, Harsharan S., Parra-Damas, Arnaldo, Mrowka, Leander, Theodorou, Delphine, Rempfler, Markus, Xavier, Anna L.R., Kress, Benjamin T., Benakis, Corinne, Steinke, Hanno, Liebscher, Sabine, Bechmann, Ingo, Liesz, Arthur, Menze, Bjoern, Kerschensteiner, Martin, Nedergaard, Maiken, Ertürk, Ali
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494982/
https://ncbi.nlm.nih.gov/pubmed/30598527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0301-3
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