Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections

Analysis of entire transparent rodent bodies after clearing could provide holistic biological information in health and disease, but reliable imaging and quantification of fluorescent protein signals deep inside the tissues remained a challenge. Here, we developed vDISCO, a pressure driven, nanobody...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Cai, Ruiyao, Pan, Chenchen, Ghasemigharagoz, Alireza, Todorov, Mihail Ivilinov, Förstera, Benjamin, Zhao, Shan, Bhatia, Harsharan S., Parra-Damas, Arnaldo, Mrowka, Leander, Theodorou, Delphine, Rempfler, Markus, Xavier, Anna L.R., Kress, Benjamin T., Benakis, Corinne, Steinke, Hanno, Liebscher, Sabine, Bechmann, Ingo, Liesz, Arthur, Menze, Bjoern, Kerschensteiner, Martin, Nedergaard, Maiken, Ertürk, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494982/
https://ncbi.nlm.nih.gov/pubmed/30598527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0301-3
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