Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections

Analysis of entire transparent rodent bodies after clearing could provide holistic biological information in health and disease, but reliable imaging and quantification of fluorescent protein signals deep inside the tissues remained a challenge. Here, we developed vDISCO, a pressure driven, nanobody...

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Publicat a:Nat Neurosci
Autors principals: Cai, Ruiyao, Pan, Chenchen, Ghasemigharagoz, Alireza, Todorov, Mihail Ivilinov, Förstera, Benjamin, Zhao, Shan, Bhatia, Harsharan S., Parra-Damas, Arnaldo, Mrowka, Leander, Theodorou, Delphine, Rempfler, Markus, Xavier, Anna L.R., Kress, Benjamin T., Benakis, Corinne, Steinke, Hanno, Liebscher, Sabine, Bechmann, Ingo, Liesz, Arthur, Menze, Bjoern, Kerschensteiner, Martin, Nedergaard, Maiken, Ertürk, Ali
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494982/
https://ncbi.nlm.nih.gov/pubmed/30598527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0301-3
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