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Revisiting the Functional Role of Dopamine D(4) Receptor Gene Polymorphisms: Heteromerization-Dependent Gain of Function of the D(4.7) Receptor Variant
The two most common polymorphisms of the human DRD4 gene encode a dopamine D(4) receptor (D4R) with four or seven repeats of a proline-rich sequence of 16 amino acids (D4.4R or D4.7R). Although the seven-repeat polymorphism has been repeatedly associated with attention deficit hyperactivity disorder...
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| Publicado en: | Mol Neurobiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6494742/ https://ncbi.nlm.nih.gov/pubmed/30387076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1413-1 |
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