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Dopamine D(4) receptor, but not the ADHD-associated D(4.7) variant, forms functional heteromers with the dopamine D(2S) receptor in the brain

Polymorphic variants of the dopamine D(4) receptor have been consistently associated with attention-deficit hyperactivity disorder (ADHD). However the functional significance of the risk polymorphism (variable number of tandem repeats in exon 3) is still unclear. Here we show that whereas the most f...

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Detalhes bibliográficos
Main Authors: González, Sergio, Rangel-Barajas, Claudia, Peper, Marcela, Lorenzo, Ramiro, Moreno, Estefanía, Ciruela, Francisco, Borycz, Janusz, Ortiz, Jordi, Lluís, Carme, Franco, Rafael, McCormick, Peter J., Volkow, Nora D., Rubinstein, Marcelo, Floran, Benjamin, Ferré, Sergi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219836/
https://ncbi.nlm.nih.gov/pubmed/21844870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2011.93
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