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Dopamine D(4) receptor, but not the ADHD-associated D(4.7) variant, forms functional heteromers with the dopamine D(2S) receptor in the brain

Polymorphic variants of the dopamine D(4) receptor have been consistently associated with attention-deficit hyperactivity disorder (ADHD). However the functional significance of the risk polymorphism (variable number of tandem repeats in exon 3) is still unclear. Here we show that whereas the most f...

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Autores principales: González, Sergio, Rangel-Barajas, Claudia, Peper, Marcela, Lorenzo, Ramiro, Moreno, Estefanía, Ciruela, Francisco, Borycz, Janusz, Ortiz, Jordi, Lluís, Carme, Franco, Rafael, McCormick, Peter J., Volkow, Nora D., Rubinstein, Marcelo, Floran, Benjamin, Ferré, Sergi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219836/
https://ncbi.nlm.nih.gov/pubmed/21844870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2011.93
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