Fetal Hyperglycemia Acutely Induces Persistent Insulin Resistance in Skeletal Muscle

Offspring exposed in utero to maternal diabetes exhibit long lasting insulin resistance, though the initiating mechanisms have received minimal experimental attention. Herein, we show that rat fetuses develop insulin resistance after only 2 days continuous exposure to isolated hyperglycemia starting...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Endocrinol
Prif Awduron: Kua, Kok Lim, Hu, Shanming, Wang, Chunlin, Yao, Jianrong, Dang, Diana, Sawatzke, Alex B., Segar, Jeffrey L., Wang, Kai, Norris, Andrew W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494731/
https://ncbi.nlm.nih.gov/pubmed/30444716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-18-0455
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