Peroxisome Proliferator-Activated Receptor γ Decouples Fatty Acid Uptake from Lipid Inhibition of Insulin Signaling in Skeletal Muscle

Peroxisome proliferator-activated receptor γ (PPARγ) is expressed at low levels in skeletal muscle, where it protects against adiposity and insulin resistance via unclear mechanisms. To test the hypothesis that PPARγ directly modulates skeletal muscle metabolism, we created two models that isolate d...

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Hlavní autoři: Hu, Shanming, Yao, Jianrong, Howe, Alexander A., Menke, Brandon M., Sivitz, William I., Spector, Arthur A., Norris, Andrew W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355543/
https://ncbi.nlm.nih.gov/pubmed/22474127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1253
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