Epitope selection for DQ2 presentation: implications for celiac disease and viral defense

We have reported that the major histocompatibility molecule HLA-DQ2 (DQA1*05:01/DQB1*02:01) is relatively resistant to HLA-DM (DM), a peptide exchange catalyst for MHC class II. Here, we analyzed the role of DQ2/DM interaction in the generation of DQ2-restricted gliadin epitopes, relevant to celiac...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hung, Shu-Chen, Hou, Tieying, Jiang, Wei, Wang, Nan, Qiao, Shuo-Wang, Chow, I-Ting, Liu, Xiaodan, van der Burg, Sjoerd H., Koelle, David M., Kwok, William W., Sollid, Ludvig M., Mellins, Elizabeth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494460/
https://ncbi.nlm.nih.gov/pubmed/30926644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801454
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