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RNase P-mediated inhibition of cytomegalovirus protease expression and viral DNA encapsidation by oligonucleotide external guide sequences

External guide sequences (EGSs) are oligonucleotides that consist of a sequence complementary to a target mRNA and recruit intracellular RNase P for specific degradation of the target RNA. In this study, DNA-based EGS molecules were chemically synthesized to target the mRNA coding for the protease o...

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Autors principals: Dunn, Walter, Trang, Phong, Khan, Umair, Zhu, Jiaming, Liu, Fenyong
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC64944/
https://ncbi.nlm.nih.gov/pubmed/11742095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261560598
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