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Effective inhibition of human cytomegalovirus gene expression and growth by intracellular expression of external guide sequence RNA

RNase P complexed with external guide sequence (EGS) represents a novel nucleic-acid-based gene interference approach to modulate gene expression. In this study, a functional EGS RNA was constructed to target the overlapping mRNA region of two human cytomegalovirus (HCMV) capsid proteins, the capsid...

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Detalhes bibliográficos
Main Authors: LI, HONGJIAN, TRANG, PHONG, KIM, KIHOON, ZHOU, TIANHONG, UMAMOTO, SEAN, LIU, FENYONG
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2006 by RNA Society 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370886/
https://ncbi.nlm.nih.gov/pubmed/16301604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2184706
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