A‐85380: A Pharmacological Probe for the Preclinical and Clinical Investigation of the α(4)β(2) Neuronal Nicotinic Acetylcholine Receptor

A‐85380 [3‐(2(s)‐azetidinylmethoxy) pyridine] is a neuronal nicotinic acetylcholine receptor (nAChR) agonist that has been a useful tool in the investigation of the function of nAChRs in both preclinical and clinical studies. Amongst nAChR subtypes, A‐85380 shows selectivity for the α(4)β(2) vs. the...

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Publicado en:CNS Drug Rev
Autores principales: Rueter, Lynne E., Donnelly‐Roberts, Diana L., Curzon, Peter, Briggs, Clark A., Anderson, David J., Bitner, Robert S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Inc 2006
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494138/
https://ncbi.nlm.nih.gov/pubmed/16958984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2006.00100.x
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